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VOL. 10, ISSUE 2 (2026)
Phytochemical screening and antimalarial potency of Mimosa pigra L. (Fabaceae) on Plasmodium Falciparum strains at varying concentration
Authors
Adamu Danlami Mohammed, Bello Bashir Maifada, Ahmad Muhammad, Abdulwasiu Rabiu
Abstract
Malaria remains a significant global health
burden, causing disease in approximately 15.5 million people and resulting in
1–3 million deaths annually, predominantly among young children. The
development of effective antimalarial agents remains a critical priority in
combating this disease. This study evaluated the phytochemical composition and in-vitro
antimalarial activity of Mimosa pigra L. (Fabaceae) leaf extract against
Plasmodium falciparum. Dried leaf material was extracted using ethanol,
and the crude extract was subjected to phytochemical screening following
standard protocols. The antimalarial efficacy was assessed at varying
concentrations using an in-vitro culture method. Phytochemical analysis
revealed the presence of seven secondary metabolites: carbohydrates, reducing
sugars, saponins, alkaloids, flavonoids, tannins, and terpenes. The extract
demonstrated potent antimalarial activity, achieving parasitic elimination
rates of 84.8% and 80.9% at concentrations of 5,000 µg/mL and 2,000 µg/mL,
respectively. These findings suggest that the bioactive secondary metabolites
present in M. pigra may contribute to its antimalarial properties, supporting
the traditional use of this plant in the treatment of malaria in Northern
Nigeria.
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Pages:109-112
How to cite this article:
Adamu Danlami Mohammed, Bello Bashir Maifada, Ahmad Muhammad, Abdulwasiu Rabiu "Phytochemical screening and antimalarial potency of <i>Mimosa</i><i> pigra</i> L. (Fabaceae) on <i>Plasmodium Falciparum</i> strains at varying concentration". International Journal of Chemistry Studies, Vol 10, Issue 2, 2026, Pages 109-112
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