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VOL. 10, ISSUE 2 (2026)
A study for commercial exploitation exposed to some chemical mutagens, viz.: L-methionine-DL-sulfoximine(MSO), maleic hydrazide (MH), diethylnitrosamine (DEN), furylfuramide(FF)
Authors
Dr. Sujeet Kumar
Abstract
Chemical mutagens are substances that can induce genetic mutations,
chromosomal abnormalities, and carcinogenesis, which are critical concerns in
environmental, industrial, and public health domains. This study focuses on
four chemical mutagens L‑methionine‑DL‑sulfoximine (MSO), (MH), (DEN), and
furylfuramide (FF). These agents are studied for their biological effects,
mutagenic potential, and commercial use in various fields such as research,
agriculture, and food preservation. MSO is primarily used in research to
inhibit the enzyme glutamine synthetase, affecting nitrogen metabolism and
causing neurotoxic effects like excitotoxicity in neural cells. MH is a plant
growth regulator used in agriculture to prevent sprouting in crops like
potatoes and onions. However, it exhibits mutagenic properties, particularly
affecting cell division and growth processes. DEN, a potent carcinogen, is
frequently used in animal models to induce liver cancer, providing insights
into carcinogenesis and cancer therapies. FF, previously used as a food
preservative, was withdrawn from the market due to its strong mutagenic and
carcinogenic effects. The study emphasizes the importance of understanding the
mechanisms of action of these mutagens, as well as their potential commercial
applications and risks. It highlights the need for regulatory oversight to
minimize human and environmental exposure. Additionally, it calls for the
development of safer alternatives to reduce the risks posed by these chemicals
in agricultural, industrial, and food-related practices. Proper safety
standards and continuous research are crucial in mitigating the hazards
associated with these mutagenic agents.
Pages:32-36
How to cite this article:
Dr. Sujeet Kumar "A study for commercial exploitation exposed to some chemical mutagens, <i>viz</i>.: L-methionine-DL-sulfoximine(MSO), maleic hydrazide (MH), diethylnitrosamine (DEN), furylfuramide(FF)". International Journal of Chemistry Studies, Vol 10, Issue 2, 2026, Pages 32-36
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