ARCHIVES
VOL. 10, ISSUE 1 (2026)
Microwave-assisted synthesis, characterization, and computational studies of Co(II), Ni(II), and Cu(II) metal complexes with a schiff base derived from 1h-Indole-2,3-dione and 3-Chloro-4-Fluoro aniline
Authors
Priti Shrivastava, Dinesh Kumar Mishra, Samit Kumar, Awanish Kumar Patel, Ashish Sohgaura
Abstract
Metal complexes have been particularly successful and shown great
potential mainly because of their ability to have different coordination
geometries and to be more antimicrobial, antioxidant, catalytic, and
enzyme-inhibitory than the ligands they are derived In this context, the
current research focuses on the development and characterisation of a new
ligand (HL) and its corresponding metal complexes, which are synthesised by the
microwave-assisted method, supported by a thorough spectroscopic, analytical,
and theoretical study.To achieve this objective, the first step was to prepare
the 1H-Indole-2,3-dione and 3-Chloro-4-Fluoroaniline
(HL), and then its Co(II), Ni(II) and Cu(II), complexes were made, followed by
a detailed structure, magnetic properties and antimicrobial potential
characterisation of each compound. The ligand as well as metal complexes were
prepared by using standard methods and were characterised with elemental
analysis, molar conductance, FTIR, UV–Vis spectroscopy, magnetic susceptibility,
and thermo gravimetric analysis; The complexation was found to increase the
biological activity remarkably, with the Cu(II) complex exhibiting the
strongest antibacterial and antifungal activity, which was also supported by
the docking interactions. Thus, the research work not only proves that ligands
are excellent metal ion chelators for 3d metals, but at the same time, it
unlocks the way for the development of new antimicrobial drugs based on such
complexes with pharmacological properties like stability, distinct magnetism,
and high activity.
Pages:13-16
How to cite this article:
Priti Shrivastava, Dinesh Kumar Mishra, Samit Kumar, Awanish Kumar Patel, Ashish Sohgaura "Microwave-assisted synthesis, characterization, and computational studies of Co(II), Ni(II), and Cu(II) metal complexes with a schiff base derived from 1h-Indole-2,3-dione and 3-Chloro-4-Fluoro aniline". International Journal of Chemistry Studies, Vol 10, Issue 1, 2026, Pages 13-16
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