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VOL. 8, ISSUE 1 (2024)
Analysis of SGOT and SGPT levels in Wistar Rats given intake balinese Ara
Authors
I G A K S P Dewi, I Ketut Budiarta, Ni Made Suaniti
Abstract
Arak is one of Bali's typical alcoholic
beverages classified as type C. Continuous alcohol consumption can lead to
liver damage, as indicated by increased cellular enzyme activity such as SGPT
and SGOT, making SGPT and SGOT levels biochemical markers for alcohol-related
liver damage. This study aims to analyze ethanol in arak, Wistar rat serum, as
well as SGPT and SGOT levels after arak intake. Ethanol levels in arak and
serum were determined using validated Flame Ionization Detector Gas
Chromatography (GC-FID), while SGPT and SGOT levels were determined using a
photometer. The ethanol content in arak was 40.01 ± 0.01%, and the ethanol
levels in Wistar rat serum after arak intake at 40% concentration with
treatments of 0.5; 1.0; and 2,0 mL were 57.4667±0.70; 79.8083±5.89; and
133.4767±5.58 ppm, respectively. SGPT levels in serum in the arak intake
treatment groups increased within the normal range. SGOT levels in serum in the
arak intake treatment groups increased, surpassing the normal values.
Pages:23-25
How to cite this article:
I G A K S P Dewi, I Ketut Budiarta, Ni Made Suaniti "Analysis of SGOT and SGPT levels in Wistar Rats given intake balinese Ara". International Journal of Chemistry Studies, Vol 8, Issue 1, 2024, Pages 23-25
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