ARCHIVES
VOL. 8, ISSUE 1 (2024)
Synthesis, characterization, molecular docking study and anti-bacterial activity of new 4-thiazolidinone derivatives
Authors
Fadhil D Khalid
Abstract
In the current work, a series of compounds containing of thiazolidinone
derivatives (AD6-AD10) prepared by reacting Schiff base with thioglycolic acid
in dioxane and characterization by using spectroscopic techniques FT-IR, 1H-NMR,
13C-NMR and CHN spectral technique Antibacterial behaviors inspected
against various bacteria, including Staphylococcus epidermidis and Staphylococcus
aureus Gram (+) ve, Klebsiella pneumonia and Escherichia coli
Gram (-) ve. Insilico molecular docking study performed for the active
compound where the compounds showed good docking score with a good binding mods.
Pages:5-10
How to cite this article:
Fadhil D Khalid "Synthesis, characterization, molecular docking study and anti-bacterial activity of new 4-thiazolidinone derivatives". International Journal of Chemistry Studies, Vol 8, Issue 1, 2024, Pages 5-10
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