International Journal of Chemistry Studies

Authors
Sri Wardani, Ni Wayan Bogoriani, Ni Luh Rustini

Abstract
Kecombrang (Etlingera elatior Jack) is a plant with the potential for hypolipidemia. Kecombrang is reported to contain secondary metabolites in the form of tannins, saponins, alkaloids, steroids, terpenoids, phenolics, and flavonoids. This study aimed to determine the hypolipidemic activity of kecombrang flower methanol extract in obese Wistar rats fed a high-fat diet. The test animals used in this study were 18 female white rats aged two months with a weight of ± 150 grams were divided into three groups, namely normal control (only given standard feed), high-fat control (obese rats/with a high-fat diet), and flower treatment group (obese rats/with diet). high fat + flower methanol extract 100 mg/kg BW) orally for 30 days. The results were that kecombrang flowers could reduce total cholesterol levels by 55.5%; Triglycerides (TG) by 57.4%; LDL by 76.73%; and HDL by 42.96%. So we can conclude that kecombrang flowers have the potential for hypolipidemia which is characterized by decreased levels of total cholesterol, TG, and LDL and can increase cholesterol levels. HDL rat obesity (hyperlipidemia) significantly (p<0.05).