An antimicrobial is a substance that kills or inhibits the growth of microbes such as bacteria, fungi, or viruses. Antimicrobial drugs either kill microbes (microbicidal) or prevent the growth of microbes (microbistatic). Carbazole is an aromatic heterocyclic organic compound. It has a tricyclic structure, consisting of two six-membered benzene ring fused on either side of a five-membered nitrogen-containing ring. The compound's structure is based on the indole structure but in which a second benzene ring is fused onto the five-membered ring at the 2-3 position of indole Carbazole is an aromatic heterocyclic organic compound. It has a tricyclic structure, consisting of two six-membered benzene ring fused on either side of a five-membered nitrogen-containing ring. The compound's structure is based on the indole structure but in which a second benzene ring is fused onto the five-membered ring at the 2-3 position of indole Carbazole (Dibenzopyrrole) is an aromatic heterocyclic organic compound. It has a tricyclic structure, consisting of two six-membered benzene ring fused on either side of a five-membered nitrogen-containing ring. The compound's structure is based on the indole structure but in which a second benzene ring is fused onto the five-membered ring at the 2-3 position of indole. Carbazole and its derivatives are used in organic synthesis and vermicides or fungicides as they inhibit the action of certain microorganisms. Carbazole is also having the anti tubercular and anticancer activity. The microbiological assay is based upon a comparison of the inhibition of growth of micro-organisms by measured concentrations of the synthesized compound to be examined with that produced by known concentrations of a standard drugs having a know activity. Agar well diffusion method was used for anti-fungal activity. Fluconazole and Itraconazole were used as a positive control. Sample solution (1mmol) poured into the bored well. It was incubated for 4 days and it was observed after every 24 hours that there was zone of inhibition.