A novel synthesis and characterization of some azaquinazolines have been reported. 4-Nitro anilines are reacted with chloroacetyl chloride in presence of acetone to give 2-chloro-N-(4-nitrophenyl)acetamide, which when reacted with 3-amino-3,4-dihydropyrazino[2,3-b]quinolin-2(1H)-one in presence of dry pyridine to give the final target. The structures of synthesized compounds are confirmed by their IR and ¹H-NMR spectral data. Melting point of the compound has been determined by open capillary tube and hence uncorrected. TLC of the compound has been carried out by using n-hex:EA (1:1) solvent.