In this paper the calculation of the edifices have been explained in the light of molar mass, natural investigation, IR, electronic Spectra, molar conductance and attractive powerlessness. The deliberate molar conductance esteem shows that the buildings are non-electrolytic in nature. The above perception shows that Schiff bases EHPQH carry on as bidentate ligand and coordination proposes through azomethine N and oxygen particle of alcoholic gathering of ligand. The calculation of the Co (II) and Ni (II) were proposed to be octahedral in math while Cu (II) edifices were proposed to be misshaped octahedral. The Schiff bases and its edifices have been assessed for their antibacterial movement. The edifices show improved antibacterial movement than ligand. We have promoted us synthesized complexes of CO(II),Ni(II) and Cu(II) with Schiff base ligand, 2-propyl-thioquinazolin 4(3H) Semicarbazones are used as ligands in coordination chemistry and are biologically active compounds.