Amino methylation, structure and biological activity of the new mannich base derived from Maleic hydrazide and its transition metal complexes
A Balakrishnan, Dr. A Sankar
In this study, we report the synthesis of a new Mannich base derived from Maleic hydrazide and its transition metal complexes. Maleic hydrazide was aminomethylated by reacting with formaldehyde and N-methylpiperazine. The so formed base is complexed with transition metals. The structure of the synthesized compounds are confirmed by UV, IR, and 1H NMR spectroscopic techniques. The antibacterial activity of the ligands and the complexes were examined using different bacterias.