In this paper, comparative studies on the different synthesis of polystyrene spheres in aqueous water and alcohol systems were successfully developed by emulsion soap polymerization then polystyrene monolayer was obtained. Polystyrene spheres in aqueous water and alcohol systems were carried out at 80 0C temperature. Polystyrene spheres synthesis in aqueous water was given best result when comparative with alcohol soluble.
The result of enhancement of the structure, properties and characterization, and its application was found in polystyrene monolayer and drug industrial.
The characterization of polystyrene spheres and monolayer were done by SEM, TEM and XRD.