Vol. 2, Issue 2 (2018)
Synthesis, spectral characterization and biological studies on new benzothiazoles as antimicrobial agents
Author(s): B Jini Kumari, TF Abbs Fen Reji
Abstract: A series of 2-[2,4-bis(aryl/alkylamino)thiazol-5-oyl]benzothiazole derivatives were synthesized from 1-aryl-3-(N,N’-diarylamidino)thioureas and 2-(2-bromoacetyl)benzothiazole with triethylamine. Their structures were established on the basis of IR,1H NMR, 13C NMR and mass spectral analyses. All the synthesized compounds were screened for their antibacterial and antifungal potential. All the compounds showed significant activity against the microorganisms tested.