Vol. 2, Issue 1 (2018)
Formulation and evaluation of fast disintegrating tablets of ondansetron hydrochloride dihydrate using Glycine max (L.) Merr. Husk as superdisintegrant
Author(s): Ayush Garg
Abstract: The present scenario of pharmaceutical technology is changing continuously with every addition of new excipient for various solid dosage forms. Disintegrant is a common and most essential part of solid dosage forms such as tablet, capsules etc. It is an excipient in solid dosage form and has a major role to play. There are many substances act as disintegrant having advantages over each other. With the fast growing Pharma sector the number of such substances increasing day by day as per the need of industry. This makes the formulator to think over each and every aspect of the disintegrant for choosing it in his formula. Disintegrants are additives which cause a compressed tablet to break when placed in an aqueous media. Disintegrants are used to break (disintegrate) the intact tablet or capsule into smaller particulates so as to increase dissolution and increase faster action of dosage form. This alters the pharmacokinetics of dosage form.